Dr. Hemanth Rao, the president and CEO of the Neurological Institute of Charlotte, NC, also takes an active role in clinical research into treatments for brain and nerve disorders. Dr. Hemanth Rao of Charlotte, NC, has contributed to several new approaches targeting Alzheimer's disease.
In developing treatments for Alzheimer's disease, one of the most significant challenges is the blood-brain barrier. This thin membrane, designed to protect the brain from infectious agents, causes a problem for researchers in that it also prevents crucial therapeutic agents from entering the brain.
Now, however, a team of scientists from the Queensland Brain Institute has found that ultrasound waves may be effective in helping drugs to cross that barrier. The researchers were able to use scanning ultrasonography to deliver antibodies to the brains of mice exhibiting symptoms of Alzheimer's. This treatment proved effective in reducing the number of the tau proteins that contribute to disease progression, thus mitigating symptoms.
The team believes that this treatment may be similarly effective in reducing tau concentrations in human patients. If so, the technique could also prove promising in treating other neurological conditions, such as multiple sclerosis and Parkinson's disease.
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